Exocrine pancreatic insufficiency (EPI)
It is the inability to properly digest food due to a lack of digestive enzymes made by the pancreas. EPI is found in humans afflicted with cystic fibrosis and Shwachman– Diamond syndrome
What are the symptoms of exocrine pancreatic insufficiency?
- Frequent diarrhea. EPI can cause problems with undigested food moving too quickly through the digestive tract.
- Gas and bloating. ...
- Stomach pain. ...
- Foul-smelling, greasy stools (steatorrhea) ...
- Weight loss.
How do you test for pancreatic insufficiency?
- Fecal elastase test. This test measures the amount of elastase, an enzyme produced by the pancreas, in your stool. ...
- Fecal fat test. This test checks the amount of fat in your stool. ...
- Direct pancreatic function test.
Symptoms and Signs :
- anemia (Vitamin B12, iron, folate deficiency)
- bleeding disorders (Vitamin K malabsorption)
- edema (hypoalbuminemia)
- fatigue
- flatulence and abdominal distention (bacterial fermentation of unabsorbed food)
- hypocalcemia
- metabolic bone disease (Vitamin D deficiency)
- neurologic manifestation
- steatorrhea
- weight loss
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