#ClinicalGastro2019 #Liver #LiverFunctionTest #Liver function tests , also referred to as a #hepatic panel, are groups of #blood tests that provide information about the state of a #patient's liver.
These tests include prothrombin time
(PT/INR), aPTT, albumin, bilirubin (direct and indirect), and others. The liver transaminases aspartate transaminase (AST or SGOT)
and alanine transaminase (ALT or SGPT)
are useful biomarkers of liver injury in a patient with some degree of intact liver function. Most liver diseases
cause only mild symptoms initially, but these diseases must be detected early. Hepatic (liver) involvement in some diseases can be of crucial importance. This testing is performed on a patient's blood sample. Some tests are associated with functionality (e.g., albumin), some with cellular integrity (e.g., transaminase
), and some with conditions linked to the biliary tract (gamma-glutamyl transferase
and alkaline phosphatase
). Several biochemical tests are useful in the evaluation and management of patients with hepatic dysfunction. These tests can be used to detect the presence of liver disease, distinguish among different types of liver disorders, gauge the extent of known liver damage, and monitor the response to treatment. Some or all of these measurements are also carried out (usually about twice a year for routine cases) on those individuals taking certain medications, such as anticonvulsants, to ensure that the medications are not adversely impacting the person's liver.
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